It may be significant that a key difference between marsupials and Eutherians is the extent to which extra embryonic tissues support growth in utero with the Eutherian newborn being substantially larger at term, relative to the size of the mother, and distinctly more mature than the marsupial newborn.
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Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta.
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