Similarly, no major differences in histamine-metabolizing genes were observed, with the exception of a marginally significant lower frequency of homozygous variant genotypes corresponding to the DAO gene variation rs10156191 among patients, which was not significant on comparing allele frequencies (Table 6 ).
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FCERI and Histamine Metabolism Gene Variability in Selective Responders to NSAIDS.
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The sentences
The observed difference was related to the frequency of homozygous individuals for the minor allele, which obtained a marginal significance that was not observed when the allele frequency (instead of the genotypes) was analyzed.