Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model.

Sci Rep · 2016 · PMC5041108 · PMID 27681803

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not yet significantno p-value reported

Further to this, our results suggest a threshold of amyloid buildup required to influence 5-mC levels as at two months of age, the difference in methylation between Tg and control animals is not yet significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.