highly significantP < 0.001
In the statistical analyses, differences were classed as significant (*) for values of P < 0.05, more significant (**) for values of P < 0.01, and highly significant (***) for values of P < 0.001.
In the statistical analyses, differences were classed as significant (*) for values of P < 0.05, more significant (**) for values of P < 0.01, and highly significant (***) for values of P < 0.001.