A borderline significant relative survival benefit was observed in MET-treated patients compared with non-MET-treated patients [hazard ratio (HR), 0.80; 95% confidence interval (CI), 0.62–1.03] in a pooled analysis of four publications containing 1,429 patients ( 33 ).
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Inhibitory effect of metformin combined with gemcitabine on pancreatic cancer cells in vitro and in vivo.
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