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Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer.

Cancer Metab · 2016 · PMC5046889 · PMID 27729975

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While we did not observe significant changes in GSH content in cells (data not shown), we did observe modest increases in ROS, albeit not quite statistically significant (Additional file 2 : Figure S2b).

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