Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

Breast Cancer Res · 2016 · PMC5048645 · PMID 27716369

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marginally significantno p-value reported

The marginally significant increased risk of locoregional relapse associated with p.I157T in the adjusted analyses (hazard ratio 1.62 [0.99 - 2.66], p value 0.056) warrants further studies, but could merely reflect the baseline risk associated with p.I157T: some of the local recurrences could represent new cancers arising during the 10-year follow-up.

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