An analysis of studies using ≥60% EPA resulted in a highly significant pooled SMD estimate, whereas studies using ≤60% EPA found no significant antidepressant effects [ 59 ]. 3.3.3.
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Inflammation in Depression and the Potential for Anti-Inflammatory Treatment.
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Four trials have investigated their antidepressant effects and found borderline significance towards a better antidepressant effect compared to placebo [ 7 ].