DNA Methylation Patterns in Rat Mammary Carcinomas Induced by Pre- and Post-Pubertal Irradiation.

PLoS One · 2016 · PMC5053445 · PMID 27711132

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The global DNA hypomethylation was observed across all of the spontaneous and radiation-induced carcinomas; however, there was a set of 44 genes which showed highly significant tumor-specific increases in DNA methylation (with changes in gene expression) that were enriched for cellular differentiation, development and transcription factor activity.

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