In contrast, nononcogenic HPV infections showed an increasing trend in the same calendar period.
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Human Papillomavirus Infections are Common and Predict Mortality in a Retrospective Cohort Study of Taiwanese Patients With Oral Cavity Cancer.
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Such an increase was largely driven by HPV-related OPC from 1983 to 2002, whereas OCC concomitantly showed a decreasing trend. 4 , 5 In general, the role of HPV infections in the pathogenesis of OCC seems to be less prominent in industrialized countries. 6 Despite the reduction in risky oral habits (ie, betel chewing, tobacco smoking, and alcohol drinking) observed between 1980 and 2010, the incidence of OCC in Taiwan is