Loss of immune tolerance to IL-2 in type 1 diabetes.

Nat Commun · 2016 · PMC5059699 · PMID 27708334

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highly significantno p-value reported

While the highly significant association between free soluble anti-rhIL-2 autoantibodies and T1D is remarkable, the functional capacity of these antibodies—at the monoclonal level—to neutralize or otherwise modulate IL-2 function remains to be assessed.

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