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Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression - implications for atherosclerosis research.

Sci Rep · 2016 · PMC5062347 · PMID 27734926

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an overall trendno p-value reported
Thus, both M1 and M2 genes are expressed in atherosclerotic lesions both early and late, and an overall trend towards downregulation of M2-associated genes was observed with disease progression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.