Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids.

Nucleic Acids Res · 2016 · PMC5063000 · PMID 27574117

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highly significantno p-value reported

Importantly, anti-R-loop immunofluorescence followed by single cell analysis revealed that knockdown of human ATXN2 results in a highly significant nuclear R-loop accumulation (Figure 4C , Supplementary Figure S4C).

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