There were no demonstrable benefits in premenopausal women but in 11,767 postmenopausal women, highly significant reductions in bone recurrence (RR=0.72; 95%CI 0.60–0.86, 2p=0.0002) and breast cancer mortality (0.82; 95%CI 0.73–0.93, 2p=0.002) were seen.
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