HIV Drug Resistance in Antiretroviral Treatment-Naïve Individuals in the Largest Public Hospital in Nicaragua, 2011-2015.

PLoS One · 2016 · PMC5063387 · PMID 27736898

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an increasing trendno p-value reported

Although it is true that part of the increasing trend in PDR was due to an increasing trend observed in E138A frequency ( Fig 5 ), affecting RPV and ETR (drugs not used in Nicaragua), PDR to the two most common first-line ART regimens in Nicaragua reached important levels in 2015: 14.6% to AZT + 3TC + EFV and 10.4% to TDF + FTC + EFV.

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