Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study.

J Transl Med · 2016 · PMC5064898 · PMID 27737711

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highly significantno p-value reported

Noteworthy, the impact on OS and TTPM of the BRAF mutations was so highly significant to negatively affect such survivals in the combined group of mutated patients (considering all mutations in RAS and BRAF genes) (Table 3 ).

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