Interestingly, when we crossed our RNA-seq data of Setdb1 knockdown ( Supplementary Table S2 ) with microarray data of proliferating myoblasts treated with Wnt3a [ 59 ], we obtained a highly significant overlap of commonly deregulated genes ( Figure 6b ).
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Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation.
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