60 , 61 Both data sets showed a significant decreased expression of FGF14 , PVALB , GAD67 and VGAT ( Figure 5a and Supplementary Figure 6 ), and a highly significant correlation between FGF14 , PVALB , GAD67 and VGAT was found in all samples and in schizophrenia alone with the largest effect size in schizophrenia and controls for GAD67 ( Figure 5b ).
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Genetic deletion of fibroblast growth factor 14 recapitulates phenotypic alterations underlying cognitive impairment associated with schizophrenia.
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