Biodistribution of Idursulfase Formulated for Intrathecal Use (Idursulfase-IT) in Cynomolgus Monkeys after Intrathecal Lumbar Administration.

PLoS One · 2016 · PMC5072681 · PMID 27764180

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may be significantno p-value reported

Transposed to a human, clinical environment, this may be significant in terms of potentially helping to ameliorate the somatic symptoms of patients with Hunter syndrome undergoing intrathecal idursulfase enzyme replacement therapy [ 11 ].

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