Effects of Ginkgo biloba extract EGb 761® on cognitive control functions, mental activity of the prefrontal cortex and stress reactivity in elderly adults with subjective memory impairment - a randomized double-blind placebo-controlled trial.

A 2 × 2 × 2 repeated measures ANOVA with Time (pre/post‐treatment) and Trial‐Type (repeat/switch) as within‐subjects variables, Group (verum/placebo) as between‐subjects variable and mean RT as the dependent variable yielded highly significant effect of Time, F (1,57) = 39.05, p < 0.001, η 2 = 0.41, reflecting practice effects and Trial‐Type, F (1,57) = 92.55, p < 0.01, η 2 = 0.62, reflecting increased RT for task switch trials.

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A nonsignificant trend indicated a potentially accelerated endocrine stress recovery.

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