highly significantp < 0.0001
A meta-analysis based mainly on the findings of six studies pertaining to treatment with clozapine supported a significant overall beneficial effect on suicidal behavior, with a highly significant ( p < 0.0001), 3.3-fold [CI: 1.7–5.7] lower pooled risk of suicidal behaviors with clozapine compared to alternative treatments [ 41 ].