Occurrence of Anti-Drug Antibodies against Interferon-Beta and Natalizumab in Multiple Sclerosis: A Collaborative Cohort Analysis.

PLoS One · 2016 · PMC5091903 · PMID 27806057

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

borderline significantp = 0.06so close (0.05 < p ≤ 0.1)

In Austria, Germany and Denmark, male patients had an immune response to IFNβ more frequently than females, this association between sex and ADA being significant in Austria and in Germany–Munich group (p < 0.01), and borderline significant for Denmark (p = 0.06).

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at the limit of significanceno p-value reported

The adjusted HRs for males compared to females were significant in Austria (1.4, 95% CI 1.1–1.9) and Denmark (1.6, 95% CI 1.0–2.7), at the limit of significance in Germany-Dusseldorf (1.4, 95% CI 0.9–2.0) and not significant in Sweden (1.0, 95% CI 0.7–1.3) ( Table 3 and Fig 4 ).

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