Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice.

The average threshold for suggestive, significant, and highly significant linkages were LOD ≥ 2.1 ( p ≤ 7.8 × 10 −3 ), LOD ≥ 3.6 ( p ≤ 2.4 × 10 −4 ), and LOD ≥ 5 ( p ≤ 1 × 10 −5 ), respectively ( Manly and Olson 1999 ).

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