highly significantP = 0.006
A clustering analysis of the pairwise correlations of the positive or negative genetic interactions of the 65 ribosomal proteins ( Fig 2B ) identified three clusters, which had a highly significant overlap with the previous clustering based on phenotypic profiling (90% overlap between Clusters 1 and A and 89% between clusters 2 and B, Fisher Exact test, P = 0.006, S4 Table ).