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Widespread use of gastric acid inhibitors in infants: Are they needed? Are they safe?

World J Gastrointest Pharmacol Ther · 2016 · PMC5095572 · PMID 27867686

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a definite trendno p-value reported
Whilst there is no contemporary data outlining the relative frequency of H2RA and PPI use, the authors have observed a definite trend towards PPI as the predominant medication prescribed or acid suppression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.