Which plays a predominant role in the maintenance of skeletal muscle homeostasis involved in the mechanism of protecting from muscle atrophy during prolonged disuse in hibernation, the increase of protein synthesis or the decrease of protein degradation? It is noteworthy that the protein biosynthesis category by overexpressed genes exhibits a highly significant enrichment in skeletal muscle of hibernating black bears ( Ursus americanus ) [ 18 ].
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iTRAQ-based proteomic analysis of myofibrillar contents and relevant synthesis and proteolytic proteins in soleus muscle of hibernating Daurian ground squirrels (<i>Spermophilus dauricus</i>).
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