MCP-1 showed a higher concentration in mice exposed to DFO treated cells and IL-6 further exhibited a highly significant increase of expression in DFO exposed cells in comparison to those treated in environmental hypoxic or normoxic conditions ( Fig. 4 ).
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VEGF released by deferoxamine preconditioned mesenchymal stem cells seeded on collagen-GAG substrates enhances neovascularization.
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