marginally significantP = 0.05
Oral contraceptives Of 11 IBWIL studies assessing oral contraceptives [ 21 , 26 , 27 , 29 , 38 , 39 , 42 , 51 – 53 , 55 , 56 , 58 ], one reported a marginally significant increase in risk (adjHR: 1.46, P = 0.05); 10 reported nonsignificant estimates ranging from adjusted incidence rate ratios (adjIRR) 0.66 to adjHR 1.80 (Fig. 2 ).