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The Effects of Pharmacological Compounds on Beat Rate Variations in Human Long QT-Syndrome Cardiomyocytes.

Stem Cell Rev Rep · 2016 · PMC5106508 · PMID 27646833

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a slightly increasing trendno p-value reported
We noted a slightly increasing trend of BR with increasing bisoprolol concentration in the hiPSC-CMs from asymptomatic mutation carrier (15 % for 303.LQT1 and 19 % for 313.LQT1).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.