Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance.

Nat Commun · 2016 · PMC5114538 · PMID 27841270

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highly significantno p-value reported

Despite this rescue of centromeric transcription, we observed a highly significant drop in CENP-A and CENP-C levels on the alphoid tetO HAC centromere at 2 and 4 days after transfection of tetR-EYFP-LSD2 WT plus tetR-mCherry-CENP-28/Eaf6 compared with control experiments ( Fig. 5e,f ; Supplementary Fig. 5f,g ).

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