Preventing painful age-related bone fractures: Anti-sclerostin therapy builds cortical bone and increases the proliferation of osteogenic cells in the periosteum of the geriatric mouse femur.

Mol Pain · 2016 · PMC5117249 · PMID 27837171

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In the geriatric animals, there was also a highly significant increase when comparing vehicle vs. anti-sclerostin (5.6% to 16.6%) in the number of newborn BrdU+ cells in the cambium layer ( Figure 5(a) ).

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