Barely Significant
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Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons.

Nat Commun · 2016 · PMC5118542 · PMID 27853135

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highly significantP <<0.001actually significant
5c ; normalized frequency following light activation=15.3±2.8%; highly significant difference from 100%, P <<0.001) and the intensity of the responses to electrical stimulation ( Fig. 5d ; Normalized power, VU, 38.4±12.4; VU+light, 6.1±2.1; P <0.05), even in the continued presence of perfusing VU0463271.

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