Augmentation of histone deacetylase 3 (<i>HDAC3</i>) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes.

Clin Epigenetics · 2016 · PMC5122206 · PMID 27904654

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an increasing trendno p-value reported

5 ) while both the expression levels of TNF-α and IL-6 showed an increasing trend but not statistically significant.

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highly significantno p-value reported

As the highly significant HDAC3 mRNA expression was the prominent finding in our study in PBMCs from patients with type 2 diabetes, we then analyzed the specific HDAC3 activity in the study samples.

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