Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management.

BMC Bioinformatics · 2016 · PMC5123238 · PMID 28185542

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an increasing trendno p-value reported

Coverage was evaluated as defined in Methods section and the percentage of not covered base pairs varied from 3.4 % (for COL4 panel) to 9.2 % (for Parkinson panel), showing an increasing trend with panel dimension (R2 = 0.5222, see Additional file 1 : Figure S2B and Table S2 for details).

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