Assessment of cardiac resynchronisation therapy in patients with wide QRS and non-specific intraventricular conduction delay: rationale and design of the multicentre randomised NICD-CRT study.

For a two-sided type I error at 5% and a statistical power equals 90%, n=86 randomised patients will allow highlighting a clinical and realistic effect-size of 0.5 which could be considered significant according to Cohen's recommendations (Statistical power analysis for the behavioural sciences (2nd edn).

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