Polygenic profile scores, calculated using marker weights from the social deprivation GWAS in UK Biobank, produced highly significant associations at each p value threshold with SIMD in GS:SFHS, with the most predictive score being that which was derived using all SNPs (β = 0.079, SE = 0.008, r 2 = 0.008, p = 2.26 × 10 −5 ).
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Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank.
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