In this study, other sample features such as LOH in 2p, 5q, 17q, and 18q, the extent of CIMP and MSI phenotypes were also evaluated, and a highly significant association between Aurora-A overexpression and CIN (defined as the presence of LOH in any of the chromosomal segments) was found.
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The more the messier: centrosome amplification as a novel biomarker for personalized treatment of colorectal cancers.
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