In FL and in many other cancers, there was a highly significant excess of mutations in WR C G/C G YW compared to the motifs lacking WRC ( Table 2 ) indicating that the overlap of the AID motif and CpG indeed is the unique mutagenesis signature.
← all excerpts
Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers.
1
—
—