Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65.

Gene Ther · 2016 · PMC5143366 · PMID 27653967

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

did not quite reach significanceP =0.058so close (0.05 < p ≤ 0.1)

Although this did not quite reach significance ( P =0.058) it indicated that AAV2/5 was likely to be a more effective serotype for the transduction of human RPE.

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