After adding the latter QTL to the MQM model, I performed a pair-wise test for epistasis between all QTL pairs, and uncovered a marginally significant interaction between the chromosome 2 QTL ( Q 1 ) and the centromeric QTL on chromosome 5 ( Q 5 ).
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Multiple Genes Cause Postmating Prezygotic Reproductive Isolation in the Drosophila virilis Group.
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The sentences
This QTL remains highly significant with up to four covariate markers, but the addition of the fifth marker (the adjacent Q3 at 116 cM) renders it nonsignificant.