Defective Acetylcholine Receptor Subunit Switch Precedes Atrophy of Slow-Twitch Skeletal Muscle Fibers Lacking ERK1/2 Kinases in Soleus Muscle.

Sci Rep · 2016 · PMC5146667 · PMID 27934942

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0.0700

closest p · 1.4× alpha

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boldest claim

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almost reached statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Staining for AChRε at this early age showed a statistically significant increase in AChRε-/SV2+ NMJs in DKO muscle relative to control (13.4 ± 2.4% and 4.2 ± 2.2%, respectively; p = 0.008) and a corresponding reduction in AChRε+/SV2+ endplates (89.4 ± 4.5% control, 79.6 ± 5.2% DKO) that almost reached statistical significance (p = 0.07) ( Fig. 8c and d).

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