Getting to the heart of intracellular glucocorticoid regeneration: 11β-HSD1 in the myocardium.

J Mol Endocrinol · 2017 · PMC5148800 · PMID 27553202

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failed to reach significanceno p-value reported

In clinical trials of 11β-HSD1 inhibitors in diabetes, improvement in blood glucose and other metabolic end points failed to reach significance when compared with existing therapies, but the evidence for a modest benefit was highly consistent ( Anderson & Walker 2013 ).

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