Replication of Caucasian Loci Associated with Osteoporosis-related Traits in East Asians.

First, the associations of the selected risk alleles were marginally significant [α (significance level of Bonferroni correction for multiple testing < P <0.05; α=0.05/35 SNPs/three genetic models=0.00048).

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A risk allele was an allele associated with a decreased BMD, increased risk of osteoporosis, or fracture at vertebral, non-vertebral, and any sites, with marginal significance if the P values were lower than 0.05 but higher than α, significance level of Bonferroni correction for multiple testing (α=0.05/35 SNPs/three genetic models=0.00048).[ 9 ] 4.

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