Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication.

J Exp Med · 2016 · PMC5154948 · PMID 27852793

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highly significantno p-value reported

Intrigued by the highly significant difference in the priming of CD8 T cells after i.vag. versus t.c. infection, we hypothesized that infection of the UFRT may result in higher induction of local IFN and subsequent inflammation that leads to local maturation of APCs.

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