highly significantP<0.005
As shown in Fig 4A , RGDS-FNIII9/10 coated PLA-nanoparticles bound more or were more endocytosed by HT-1080 than KGES-FNIII9/10 particles (twice) and blank nanocarriers (8 times), but the difference was only highly significant (P<0.005) at the highest concentration (1 million PLA nanoparticles/cell).