PureCN: copy number calling and SNV classification using targeted short read sequencing.

Source Code Biol Med · 2016 · PMC5157099 · PMID 27999612

Europe PMC DOI

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closest p · 0.0× alpha

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of borderline significanceP > 0.001actually significant

Breakpoints of borderline significance ( P > 0.001) are removed in our default segmentation when mirrored allelic fractions (1- allelic fraction if allelic fraction >0.5) of known heterozygous germline variants (dbSNP) are not significantly different ( P > 0.2, two-sided t -test) in the corresponding neighboring segments.

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