Symptom profiles of subsyndromal depression in disease clusters of diabetes, excess weight, and progressive cerebrovascular conditions: a promising new type of finding from a reliable innovation to estimate exhaustively specified multiple indicators-multiple causes (MIMIC) models.

Family history of alcohol or drug use is a highly significant risk factor (odds ratio 4.42) in distinguishing patients with vascular depression from those with non-vascular depression. 19 Therefore, a dummy variable, alcohol, was created to reflect high alcohol consumption based on the summative frequencies of beer, wine, and liquor consumed in the past month.

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However, other researchers challenge the pre-occupation with co-morbid major depression in diabetes, maintaining that in many situations, subsyndromal depressive symptoms, and even subthreshold symptoms that are approaching clinical significance, are non-pathological manifestations of distress in coping with illness-specific stressors and other life stressors that impinge on an individual’s capacity to manage their illness. 11 – 14 Difficulties with glycemic control, for instance, occur at all levels of depressive symptoms, even at low lev

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The fact that this outcome did not occur suggests that there may be significant scope for alexithymia within specific metabolic/vascular subgroups.

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