Time Series miRNA-mRNA integrated analysis reveals critical miRNAs and targets in macrophage polarization.

Sci Rep · 2016 · PMC5159803 · PMID 27981970

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a decreasing trendno p-value reported

Cluster 1 has a decreasing trend of gene expression, with enriched pathways in signal transduction and immune response.

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an increasing trendno p-value reported

Cluster 2 has an increasing trend and is also enriched with pathways for immune response and antigen processing and presentation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.