Prospective open-label study of add-on and monotherapy topiramate in civilians with chronic nonhallucinatory posttraumatic stress disorder.

Predictors of discontinuation There were no statistically significant predictors of panic-like adverse events resulting in discontinuation from the study (age, sex, symptom duration, age at onset, bipolarity, substance abuse, baseline severity of illness), although the coadministration of a benzodiazepine nearly reached significance (Fisher exact test, P = 0.05).

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