Epigenetic biomarkers in progression from non-dysplastic Barrett's oesophagus to oesophageal adenocarcinoma: a systematic review protocol.

BMJ Open · 2016 · PMC5168625 · PMID 27927666

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may be significantno p-value reported

We anticipate that due to the difficulty in obtaining samples and the length of follow-up required to assess progression from BO to OADC, there may be significant sample selection bias.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.